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发布于:2018-3-9 11:11:50  访问:4 次 回复:0 篇
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The Way To Turbo-Charge PTPRJ Within Five Seconds
Significantly fewer (P < 0.05) eyes experienced hypotony in the device group (4%, 3 of 76) than the trabeculectomy group (14%, 11 of 77). All other complications (bleb leak, shallow anterior chamber, choroidal effusion, hypotony, maculopathy, and hyphema) were similar between groups. No significant difference was observed in the number of laser suture lysis procedures performed between groups (n = 34, device group; n = 41, trabeculectomy group), in the number of times 5-fluorouracil was administered (n = 2 each group), or in the number of times bleb needling was performed (n = 1 each group). Sugiyama and colleagues conducted a pilot case series of 21 eyes of Japanese patients with open-angle glaucoma, with 10 eyes receiving EX-PRESS device implantation and 11 undergoing trabeculectomy.30 Three eyes in each group had concurrent cataract surgery. PTPRJ Etoposide mw Mean IOP was similar between groups at 6, 9, and 12?months postoperatively. At a follow-up of 1?year, qualified success rates (defined as IOP �� 5?mm Hg and ��21?mm Hg at 1-, 3-, 6-, 9-, and 12-month time points with or without IOP-lowering medications and without further glaucoma surgery or total loss of vision) were 100% (10 of 10) for the device group and 82% (9 of 11) for the trabeculectomy group. The difference did not reach statistical significance (P = 0.17). At 1 year after surgery, eyes in the device group required a numerically, but not significantly (P = 0.11), lower mean number of IOP-lowering medications (0.6 �� 1.1) compared with the Roxadustat purchase trabeculectomy group (1.4 �� 1.2). No significant differences were observed between groups for any of the reported complications: shallow anterior chamber, hypotony, choroidal detachment, hyphema, bleb leak, endophthalmitis, fall in visual acuity by 2 or more decimal levels, or glaucoma progression; however, both reduced visual acuity (1 out of 10 cases in the EX-PRESS group vs 5 out of 11 cases in the trabeculectomy group) and visual field defect progression (none in the EX-PRESS group vs 4 out of 11 cases in the trabeculectomy group) showed a tendency favoring the device group (P = 0.15 and P = 0.09, respectively). No significant difference was observed in the number of laser suture lysis procedures performed between groups (30% [3 of 10] in the device group, 64% [7 of 11] in the trabeculectomy group) or in the number of times bleb needling was performed (20% [2 of 10] in the device group, 33% [3 of 11] in the trabeculectomy group). Mean visual acuity was relatively stable in the device group, and only 1 of 10 eyes experienced a decline in visual acuity of 2 or more decimal levels. In contrast, 5 of 11 eyes exhibited a 2-decimal level or greater decline in visual acuity in the trabeculectomy group, and mean visual acuity was significantly lower than preoperative visual acuity from 1?week through 3?months in this group.
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