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发布于:2018-11-26 15:04:47  访问:32 次 回复:0 篇
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Cytoplasmic and nuclear extracts are shown in Figure four). This confirmed that
Every reaction also contained two g poly (dI-dC) carrier DNA. Lane 1, triplex DNA probe alone.Nelson et al. Molecular Cancer 2012, 11:38 http://www.molecular-cancer.com/content/11/1/Page 9 ofTable 3 (a) Spearman correlation p values of EMSA H3 values with expression of triplex DNA-binding proteins (3BP) and (b) correlations of U2AF65 expression to PSF and p54nrb expression in typical and tumor tissue extracts3BP expression correlated With EMSA H3 Normal cytoplasm Regular nucleus Normal total Tumor cytoplasm Tumor nucleus Tumor total Correlation to U2AF65 Typical cytoplasm Normal nucleus Typical total Tumor cytoplasm Tumor nucleus Tumor total 0.0028 0.015 0.016 1.8e-08 5.Cytoplasmic and nuclear extracts are shown in Figure 4).Cytoplasmic and nuclear extracts are shown in Figure 4). This confirmed that U2AF65 is present inside the H3 triplex DNA-protein complicated NVP-AEW541 InsulinReceptor observedTable two Correlation of the ratio of tumor (T) to normal (N) (T/N) EMSA H3 values for every patient with clinical capabilities: test statistics (a) by presence of illness in lymph nodes (N-Stage) and (b) by presence of metastasis in distant organs (distant metastasis)(a) Grouping Variable: presence of disease in lymph nodes (N Stage) dichotomized Ratio T/N cytoplasm Mann-Whitney U Wilcoxon W Z Asymp. Sig (2-tailed) 322.000 1025.000 -2.220 0.026 Cytoplasm tumor Mann-Whitney U Wilcoxon W Z Asymp. Sig (2-tailed) 342.500 1245.500 -1.689 0.091 Ratio T/N nucleus 313.000 1016.000 -2.345 0.019 Nucleus tumor 309.500 1212.500 -2.156 0.031 Ratio T/N total 310.500 1013.500 -2.380 0.017 Total tumor 321.000 1224.000 -1.993 0.(b) Grouping Variable: presence of metastasis in distant organs (distant metastasis)Nelson et al. Molecular Cancer 2012, 11:38 http://www.molecular-cancer.com/content/11/1/Page 8 of1,0,Tumor:normal (T/N) ratio <1,5 n = 33 >1,five n = 30 1-censored 2-censoredCumulative survival0,0,0,p = 0.0,0 0 ten 20 30 40 50 60Follow-up duration (months)Figure 3 All round Survival according to the tumor:normal (T/N) colorectal tissue nuclear triplex DNA-binding activity ratio. Cut-off = PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/28380356 1.five (rounded-up median).by EMSA (Figure 4).Cytoplasmic and nuclear extracts are shown in Figure four). This confirmed that U2AF65 is present within the H3 triplex DNA-protein complex observedTable 2 Correlation on the ratio of tumor (T) to normal (N) (T/N) EMSA H3 values for each patient with clinical functions: test statistics (a) by presence of disease in lymph nodes (N-Stage) and (b) by presence of metastasis in distant organs (distant metastasis)(a) Grouping Variable: presence of disease in lymph nodes (N Stage) dichotomized Ratio T/N cytoplasm Mann-Whitney U Wilcoxon W Z Asymp. Sig (2-tailed) 322.000 1025.000 -2.220 0.026 Cytoplasm tumor Mann-Whitney U Wilcoxon W Z Asymp. Sig (2-tailed) 342.500 1245.500 -1.689 0.091 Ratio T/N nucleus 313.000 1016.000 -2.345 0.019 Nucleus tumor 309.500 1212.500 -2.156 0.031 Ratio T/N total 310.500 1013.500 -2.380 0.017 Total tumor 321.000 1224.000 -1.993 0.(b) Grouping Variable: presence of metastasis in distant organs (distant metastasis)Nelson et al.
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